GRM8 anticorps (C-Term)

N° du produit ABIN357164

L’anticorps Lapin Polyclonal anti-GRM8 a été validé pour WB et EIA. Il convient pour détecter GRM8 dans des échantillons de Humain et Souris.

Aperçu rapide pour GRM8 anticorps (C-Term) (ABIN357164)

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM8 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-GRM8 anticorps

Épitope: C-Term

Specificité: This antibody detects Metabotropic Glutamate Receptor 8 (GRPRC1H) at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GRPRC1H.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000Western blot 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur GRM8

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Autre désignation: mGluR8 / GRM8

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors,that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.Synonyms: GPRC1H, Metabotropic glutamate receptor 8

Poids moléculaire: 101740 Da

ID gène: 2918, 9606

UniProt: O00222

Pathways: cAMP Metabolic Process, Synaptic Membrane