WISP3 anticorps (Middle Region)

N° du produit ABIN358747

Cet anticorps Lapin Polyclonal détecte spécifiquement WISP3 dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour WISP3 anticorps (Middle Region) (ABIN358747)

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WISP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-WISP3 anticorps

Épitope: Middle Region

Specificité: This antibody reacts to WISP3.

Purification: Affinity chromatography on Protein G

Immunogène: KLH conjugated synthetic peptide selected from the center region of human WISP3

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/50 - 1/200. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur WISP3

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Autre désignation: WISP3

Sujet: WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis.Synonyms: CCN6, UNQ462/PRO790/PRO956, WISP-3, WNT1-inducible-signaling pathway protein 3

ID gène: 8838, 9606

UniProt: O95389

Pathways: Signalisation WNT, Growth Factor Binding