ACVR1C/ALK7 anticorps (N-Term)

N° du produit ABIN359225

Détail du produit anti-ACVR1C/ALK7 anticorps

Antigène: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR1C/ALK7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Activin A Receptor Type IC (ACVR1C).

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ACVR1C.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur ACVR1C/ALK7

Antigène: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Abstract: ACVR1C Produits

Synonymes: anticorps ACVRLK7, anticorps ALK7, anticorps Alk-7, anticorps C230097P10, anticorps Alk7, anticorps habrec1, anticorps activin A receptor type 1C, anticorps activin A receptor, type IC, anticorps ACVR1C, anticorps Acvr1c

Sujet: ACVR1C, a serine/threonine protein kinase, is a type I receptor for the TGFB family of signaling molecules. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. ACVR1C is a receptor for activin AB, activin B and NODAL. This protein plays a role in cell differentiation, growth arrest and apoptosis.Synonyms: ACTR-IC, ACTRIC, ALK7, Activin receptor-like kinase 7

ID gène: 130399, 9606

UniProt: Q8NER5

Pathways: Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity