MAPK10 anticorps (N-Term)

N° du produit ABIN359639

Détail du produit anti-MAPK10 anticorps

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Épitope: AA 1-30, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody Recognizes MAPK10/JNK3

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human JNK3 . Genename: MAPK10

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MAPK10

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Autre désignation: MAPK10 (MAPK10 Produits)

Synonymes: anticorps MAPK10, anticorps zgc:123234, anticorps DKFZp459H0638, anticorps Jnk3, anticorps SAPKC, anticorps SAPb, anticorps Serk2, anticorps JNK3, anticorps JNK3A, anticorps PRKM10, anticorps SAPK1b, anticorps p493F12, anticorps p54bSAPK, anticorps C230008H04Rik, anticorps JNK3B1, anticorps JNK3B2, anticorps SAPK(beta), anticorps ATMPK10, anticorps MAP kinase 10, anticorps mitogen-activated protein kinase 8 S homeolog, anticorps mitogen-activated protein kinase 10, anticorps mitogen activated protein kinase 10, anticorps MAP kinase 10, anticorps mapk8.S, anticorps MAPK10, anticorps mapk10, anticorps Mapk10, anticorps MPK10

Sujet: JNK3 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.Synonyms: JNK3A, MAP kinase p49 3F12, Mitogen-activated protein kinase 10, PRKM10, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3

ID gène: 5602, 9606

UniProt: P53779

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades