Ret Proto-Oncogene anticorps (N-Term)
Aperçu rapide pour Ret Proto-Oncogene anticorps (N-Term) (ABIN359926)
Antigène
Voir toutes Ret Proto-Oncogene (RET) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-51, N-Term
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Specificité
- This antibody recognizes Human RET (N-term).
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Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- KLH conjugated synthetic peptide between 21~51 amino acids from the N-terminal region of Human RET
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Ret Proto-Oncogene (RET)
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Autre désignation
- RET
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Sujet
- RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.Synonyms: C-ret, CDHF12, Cadherin family member 12, Proto-oncogene tyrosine-protein kinase receptor ret
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ID gène
- 5979, 9606
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UniProt
- P07949
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Pathways
- Signalisation RTK, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
Antigène
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