IL15RA anticorps (Extracellular Domain)

N° du produit ABIN360913

Cet anticorps Rat Monoclonal détecte spécifiquement IL15RA dans WB. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour IL15RA anticorps (Extracellular Domain) (ABIN360913)

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL15RA est non-conjugé

Application: Western Blotting (WB)

Clone: 6C38

Détail du produit anti-IL15RA anticorps

Épitope: Extracellular Domain

Specificité: This antibody detects IL-15Ralpha. No cross activity to other IGFBPs.

Purification: Protein A/G affinity chromatography

Immunogène: Recombinant protein of IL-15Ralpha extracellular domain.

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL15RA

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Autre désignation: IL15RA

Sujet: IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.Synonyms: IL-15R-alpha, IL-15RA, Interleukin-15 receptor subunit alpha

ID gène: 16169

NCBI Accession: NP_032384

UniProt: Q60819

Pathways: Signalistation JAK/STAT