Leptin Receptor anticorps (Extracellular Domain)

N° du produit ABIN360927

Cet anticorps anti-Leptin Receptor est un anticorps Rat Monoclonal détectant Leptin Receptor dans WB. Adapté pour Souris.

Aperçu rapide pour Leptin Receptor anticorps (Extracellular Domain) (ABIN360927)

Antigène: Leptin Receptor (LEPR)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Leptin Receptor est non-conjugé

Application: Western Blotting (WB)

Clone: 9C29

Détail du produit anti-Leptin Receptor anticorps

Épitope: Extracellular Domain

Specificité: This antibody detects Leptin receptor.

Purification: Protein A/G affinity chromatography

Immunogène: Recombinant Leptin R extracellular domain.

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Leptin Receptor

Antigène: Leptin Receptor (LEPR)

Autre désignation: CD295 / Leptin Receptor

Sujet: Leptin receptor (OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. An OB-R transcript encodes a soluble form of the receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist. Human OB-R encodes a 1 165 amino acid residue precursor protein with a 22 amino acid residue signal peptide, an 816 amino acid residue extracellular domain, a 21 amino acid residue transmembrane domain and a 303 amino acid residue cytoplasmic domain.Synonyms: DB, HuB219, LEP-R, LEPR, OB receptor, OB-R, OBR

ID gène: 16847

NCBI Accession: NP_001116371

UniProt: P48356

Pathways: Signalistation JAK/STAT, AMPK Signaling, Feeding Behaviour