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VAV1 anticorps (pTyr174)
VAV1
Reactivité: Humain, Rat, Souris
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-VAV1 anticorps
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Antigène
Voir toutes VAV1 Anticorps
VAV1
(Vav 1 Oncogene (VAV1))
Épitope
Tous les épitopes à travers VAV1 Anticorps.
pTyr174
Reactivité
Toutes les réactivités sur VAV1 Anticorps
Humain, Rat, Souris
Hôte
Toutes les hôtes sur VAV1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur VAV1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers VAV1 Anticorps
Cet anticorp VAV1 est non-conjugé
Application
Tous les applications à travers VAV1 Anticorps.
Western Blotting (WB)
Specificité
The antibody detects endogenous level of Vav only when phosphorylated at tyrosine 174.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogène
Peptide sequence around phosphorylation site of pTyr174 (E-I-Y (p) -E-D) derived from Human Vav. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotype
IgG
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Information d'application
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Indications d'application
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-VAV1 (ABIN362132)
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Sekine, Ikeda, Tsuji, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda : "Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells. " dans: Journal of immunology (Baltimore, Md. : 1950) , Vol. 183 , Issue 12 , pp. 7966-74 , (2009 ) (PubMed ).
Détails sur VAV1
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Antigène
VAV1
(Vav 1 Oncogene (VAV1))
Autre désignation
Vav (VAV1 Produits )
Synonymes
anticorps VAV, anticorps Vav, anticorps vav-T, anticorps vav guanine nucleotide exchange factor 1, anticorps vav 1 oncogene, anticorps vav guanine nucleotide exchange factor 1 L homeolog, anticorps VAV1, anticorps Vav1, anticorps vav1.L
Sujet
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation
Poids moléculaire
95 kDa
NCBI Accession
NP_005419
UniProt
P15498
Pathways
TCR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , CXCR4-mediated Signaling Events , BCR Signaling
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