VAV1 anticorps (pTyr174)

N° du produit ABIN362131

Cet anticorps Lapin Polyclonal détecte spécifiquement VAV1 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.Il a été cité dans 1 publication.

Aperçu rapide pour VAV1 anticorps (pTyr174) (ABIN362131)

Antigène: VAV1 (Vav 1 Oncogene (VAV1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VAV1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-VAV1 anticorps

Épitope: pTyr174

Specificité: The antibody detects endogenous level of Vav only when phosphorylated at tyrosine 174.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène: Peptide sequence around phosphorylation site of pTyr174 (E-I-Y (p) -E-D) derived from Human Vav. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Références pour anticorps anti-VAV1 (ABIN362131)

Sekine, Ikeda, Tsuji, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 7966-74, (2009) (PubMed).

Détails sur VAV1

Antigène: VAV1 (Vav 1 Oncogene (VAV1))

Autre désignation: Vav

Sujet: Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation

Poids moléculaire: 95 kDa

NCBI Accession: NP_005419

UniProt: P15498

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling