PKC delta anticorps (AA 643-647)

N° du produit ABIN363002

Détail du produit anti-PKC delta anticorps

Antigène: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Épitope: AA 643-647

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC delta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificité: The antibody detects endogenous level of total PKCd protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogène: Peptide sequence around AA 643-647 (R-L-S-Y-S) derived from Human PKCd. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur PKC delta

Antigène: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Autre désignation: PKCdelta (PKCd Produits)

Synonymes: anticorps MAY1, anticorps PKCD, anticorps nPKC-delta, anticorps AI385711, anticorps D14Ertd420e, anticorps PKC[d], anticorps PKCdelta, anticorps Pkcd, anticorps fb09d10, anticorps fv43b11, anticorps prkcd, anticorps wu:fb09d10, anticorps wu:fv43b11, anticorps zgc:56558, anticorps PKC-delta, anticorps may1, anticorps npkc-delta, anticorps pkc-delta2, anticorps pkcd, anticorps tpa-1, anticorps protein kinase C delta, anticorps protein kinase C, delta, anticorps protein kinase C, delta a, anticorps protein kinase C delta L homeolog, anticorps PRKCD, anticorps Prkcd, anticorps prkcda, anticorps prkcd.L, anticorps prkcd

Sujet: This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

Poids moléculaire: 78 kDa

NCBI Accession: NP_006245

UniProt: Q05655

Pathways: Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism