Phospholipase C gamma 2 anticorps (AA 1215-1219)
Aperçu rapide pour Phospholipase C gamma 2 anticorps (AA 1215-1219) (ABIN363097)
Antigène
Voir toutes Phospholipase C gamma 2 (PLCG2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1215-1219
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Specificité
- The antibody detects endogenous level of total PLC-g2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogène
- Peptide sequence around AA 1215-1219 (F-L-Y-D-T) derived from Human PLCg2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Phospholipase C gamma 2 (PLCG2)
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Autre désignation
- PLC-gamma2
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Sujet
- The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
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Poids moléculaire
- 150 kDa
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NCBI Accession
- NP_002652
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UniProt
- P16885
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Pathways
- Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
Antigène
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