Cofilin anticorps (AA 1-5)

N° du produit ABIN363152

L’anticorps Lapin Polyclonal anti-Cofilin a été validé pour WB et IHC. Il convient pour détecter Cofilin dans des échantillons de Humain, Souris et Rat. Il y a 1 publication disponible.

Aperçu rapide pour Cofilin anticorps (AA 1-5) (ABIN363152)

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Cofilin anticorps

Épitope: AA 1-5

Specificité: The antibody detects endogenous level of total cofilin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Peptide sequence around AA 1-5 (M-A-S-G-V) derived from Human cofilin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Références pour anticorps anti-Cofilin (ABIN363152)

Zhang, Luo, Wan, Wu, Laski, Chen: "Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis." dans: Development (Cambridge, England), Vol. 138, Issue 3, pp. 455-64, (2011) (PubMed).

Détails sur Cofilin

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Autre désignation: cofilin

Sujet: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Poids moléculaire: 19 kDa

NCBI Accession: NP_000213

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events