SLC22A17 anticorps (AA 476-489)

N° du produit ABIN364414

Détail du produit anti-SLC22A17 anticorps

Antigène: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Épitope: AA 476-489

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Porc, Singe, Roussette (Chauve-souris), Hamster

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A17 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human SLC22A17. This antibody is expected to recognize both reported isoforms NP_065105.2 and NP_057693.3).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Bovine, Horse, Pig (100%) Elephant, Rabbit (93%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-PETKRKLLPEVLRD from an internal region of human SLC22A17 (NP_065105.2, NP_057693.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Bovine, Horse, Pig (100%), Elephant, Rabbit (93%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (2 μg/mL), Peptide-ELISA (1:64000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2 μg/mL. Peptide ELISA: antibody detection limit dilution 1:64000. Western Blot: Preliminary experiments gave an approx 150kD band in Human Cerebellum lysates after 0.1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 57.7kD according to NP_065105.2. The 150kD band was successfully blocked by incubation with the immunizing peptide.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur SLC22A17

Antigène: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Autre désignation: SLC22A17 (SLC22A17 Produits)

Synonymes: anticorps 1700094C23Rik, anticorps 24p3R, anticorps AU041908, anticorps AW555662, anticorps BOIT, anticorps Boct, anticorps mBOCT, anticorps BOCT, anticorps NGALR, anticorps NGALR2, anticorps NGALR3, anticorps hBOIT, anticorps rBOCT, anticorps solute carrier family 22 member 17, anticorps solute carrier family 22 (organic cation transporter), member 17, anticorps solute carrier family 22, member 17, anticorps SLC22A17, anticorps Slc22a17

Sujet: Name/Gene ID: SLC22A17
Subfamily: Organic cation transporter
Family: Transporter

Synonyms: SLC22A17, 24p3 receptor, 24p3R, BOIT, BOCT, HBOIT, NGALR, NGAL receptor, NGALR2, Lipocalin-2 receptor, MBOCT, NGALR3

ID gène: 51310

NCBI Accession: NP_065105, NP_057693

UniProt: Q8WUG5

Pathways: Transition Metal Ion Homeostasis