CD28 anticorps

N° du produit ABIN370900

Cet anticorps Hamster Monoclonal détecte spécifiquement CD28 dans FACS, IP et Func. Il présente une réactivité envers Souris.

Aperçu rapide pour CD28 anticorps (ABIN370900)

Antigène: CD28

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Clone: 37-51

Détail du produit anti-CD28 anticorps

Attributs du produit: Synonyms: TP44, T-cell-specific surface glycoprotein CD28

niveau d'endotoxine: Low Endotoxin

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry. (Ref.2-5)Immunoprecipitation. (Ref.2)Functional Assay: In vitro costimulation of T cells and NK cells. (Ref.1,4,7)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing no preservatives.

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4) CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.5-8)Synonyms: T-cell-specific surface glycoprotein CD28, TP44

UniProt: P31041

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response