CD28 anticorps (Biotin)

N° du produit ABIN370906

Cet anticorps Hamster Monoclonal détecte spécifiquement CD28 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD28 anticorps (Biotin) (ABIN370906)

Antigène: CD28

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: PV-1

Détail du produit anti-CD28 anticorps (Biotin)

Attributs du produit: Synonyms: TP44, T-cell-specific surface glycoprotein CD28

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: < / = 3 μg/10^6 cells. (Ref.8-10)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4) CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. (Ref.5) CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.6-9)Synonyms: T-cell-specific surface glycoprotein CD28, TP44

UniProt: P31041

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response