TNFRSF8 anticorps (Extracellular Domain)

N° du produit ABIN370916

Détail du produit anti-TNFRSF8 anticorps

Antigène: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Épitope: Extracellular Domain

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF8 est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Specificité: This antibody is specific to Murine CD30, Mr 52 kDa (core peptide).

Attributs du produit: Synonyms: TNFRSF8, D1S166E, CD30L receptor, KI-1 antigen, Tumor necrosis factor receptorsuperfamily member 8, Lymphocyte activation antigen CD30

Purification: Purified

Immunogène: Recombinant mouse CD30 extracellular domain-mouse IgG1 fusion protein. (Ref. 1)

Clone: MCD30-1

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: < / 3 μg/10^6 cells. Functional Assay: In vitro costimulation of T cells and NK cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TNFRSF8

Antigène: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Autre désignation: CD30 (TNFRSF8 Produits)

Synonymes: anticorps CD30, anticorps D1S166E, anticorps Ki-1, anticorps Cd30, anticorps Ki, anticorps TNFRSF8, anticorps TNF receptor superfamily member 8, anticorps tumor necrosis factor receptor superfamily, member 8, anticorps TNFRSF8, anticorps Tnfrsf8

Sujet: CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (Ref.1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (Ref.1) In anti-CD3e-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-gamma production. (Ref.1) While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.Synonyms: CD30L receptor, D1S166E, KI-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8, Tumor necrosis factor receptor superfamily member 8

ID gène: 21941

UniProt: Q60846