KLRG1 anticorps (Biotin)

N° du produit ABIN371097

Détail du produit anti-KLRG1 anticorps (Biotin)

Antigène: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp KLRG1 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Specificité: This antibody reacts with Killer Cell Lectin-like Receptor G1 (KLRG1 formerly known as mouse MAFA or 2F1-Ag). It stains 30-60 % of NK1.1+CD3- splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). (Ref.1,5)

Attributs du produit: Synonyms: KLRG1, CLEC15A, MAFA, MAFAL, Mast cell function-associated antigen, MAFA-like receptor,ITIM-containing receptor MAFA-L, Killer cell lectin-like receptor subfamily G member 1,C-type lectin domain family 15 member A

Immunogène: Activated NK (A-LAK) cells from B6 (H-2b) mice. (Ref. 1)

Clone: 2F1

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur KLRG1

Antigène: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Autre désignation: KLRG1 (KLRG1 Produits)

Synonymes: anticorps KLRG1, anticorps 2F1-Ag, anticorps MAFA, anticorps MAFA-L, anticorps 2F1, anticorps CLEC15A, anticorps MAFA-2F1, anticorps MAFA-LIKE, anticorps killer cell lectin like receptor G1, anticorps killer cell lectin-like receptor subfamily G, member 1, anticorps KLRG1, anticorps Klrg1

Sujet: Killer cell lectin-like receptor G1 (KLRG1, formerly known as mouse MAFA or 2F1 Ag), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. (Ref.1,2) These ITIMs interact with the SH2 domains of protein phosphatases such as SHP1. (Ref.3,4) Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression is indirect, and can be mediated by interactions with class I-specific Ly49 inhibitory receptors. (Ref.1)Synonyms: C-type lectin domain family 15 member A, CLEC15A, ITIM-containing receptor MAFA-L, KLRG1, Killer cell lectin-like receptor subfamily G member 1, MAFA, MAFA-like receptor, MAFAL, Mast cell function-associated antigen

ID gène: 50928

UniProt: O88713