SLC6A13
Reactivité: Rat, Souris
IHC, WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Immunohistochemitsry: 1/100-1/200. Suitable in Rat cortex and retinal sections. Not Recommended for Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody undiluted (in aliquots) at-20 °C.
Antigène
SLC6A13
(Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 13 (SLC6A13))
anticorps GAT3, anticorps Gabt3, anticorps Gat2, anticorps GAT-2, anticorps GAT2, anticorps solute carrier family 6 (neurotransmitter transporter, GABA), member 13, anticorps solute carrier family 6 member 13, anticorps Slc6a13, anticorps SLC6A13
Sujet
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).Synonyms: GAT-2, Sodium- and chloride-dependent GABA transporter 2, Solute carrier family 6 member 13