SCNN1G anticorps (C-Term)

N° du produit ABIN372870

Détail du produit anti-SCNN1G anticorps

Antigène: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCNN1G est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detetcs Human SCNN1G at C-term.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide corresponding to C-terminal residues of Human SCNN1G (Amiloride- sensitive sodium channel gamma-subunit).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 5 μg/mL. Western blot: 1 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide and 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur SCNN1G

Antigène: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Autre désignation: ENAC gamma / SCNN1G (SCNN1G Produits)

Synonymes: anticorps ENaC, anticorps BESC3, anticorps ENaCg, anticorps ENaCgamma, anticorps PHA1, anticorps SCNEG, anticorps scnn1g, anticorps MGC81424, anticorps SCNN1G, anticorps enacg, anticorps gammaxENaC-A, anticorps pha1, anticorps [g]ENaC, anticorps GAMMA-ENAC, anticorps gamma XENaC, anticorps gamma-ENaC, anticorps gamma2xENaC-A, anticorps scneg, anticorps sodium channel epithelial 1 gamma subunit, anticorps sodium channel, nonvoltage-gated 1, gamma, anticorps sodium channel, non voltage gated 1 gamma subunit L homeolog, anticorps sodium channel, nonvoltage-gated 1 gamma, anticorps sodium channel, non voltage gated 1 gamma subunit S homeolog, anticorps Scnn1g, anticorps SCNN1G, anticorps scnn1g, anticorps scnn1g.L, anticorps scnn1g.S

Sujet: Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel's syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).Synonyms: Amiloride-sensitive sodium channel subunit gamma, ENaCG, Epithelial Na(+) channel subunit gamma, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG

ID gène: 6340

NCBI Accession: NP_001030

UniProt: P51170