DUSP8 anticorps (N-Term)

N° du produit ABIN374169

Détail du produit anti-DUSP8 anticorps

Antigène: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP8 est non-conjugé

Application: Western Blotting (WB)

Séquence: *AGDRLPRKVM DAK-C

Specificité: This antibody detetcs Dual specificity protein phosphatase 8 at N-term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from N Terminus of the protein sequence according to NP_004411.2 Genename: DUSP8

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 60-65 kDa bands seen in Human Heart lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur DUSP8

Antigène: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Abstract: DUSP8 Produits

Synonymes: anticorps zgc:77593, anticorps C11orf81, anticorps HB5, anticorps HVH-5, anticorps HVH8, anticorps 5530400B01Rik, anticorps AI593498, anticorps Nttp1, anticorps Hb5, anticorps M3/6, anticorps DUSP8, anticorps dual specificity phosphatase 8, anticorps dual specificity phosphatase 8a, anticorps dual specificity protein phosphatase 8, anticorps DUSP8, anticorps dusp8, anticorps dusp8a, anticorps DSP8, anticorps Dusp8, anticorps LOC615727

Sujet: DUSP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.Synonyms: Dual specificity protein phosphatase 8

ID gène: 1850

NCBI Accession: NP_004411

UniProt: Q13202