KIF5B anticorps (C-Term)

N° du produit ABIN374232

Détail du produit anti-KIF5B anticorps

Antigène: KIF5B (Kinesin Family Member 5B (KIF5B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF5B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-QPVAVRGGGG KQV

Specificité: This antibody detects KIF5B at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Cow.
Species reactivity (tested):Human, Dog.

Purification: Ammonium Sulphate precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_004512.1 Genename: KIF5B

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western blot: Approx 120 kDa band observed in Human Kidney lysates (calculated MW of110 kDa according to NP_004512.1). Recommended dilution: 0.2 - 1 μg/mL. Immunohistochemistry on paraffin sections: Human Kidney, shows perinuclear labelling ofsome glomerular cells and cytoplasmic staining of renal tubules. Recommended concentration: 1 - 2 μg/mL. In paraffin embedded Human Uterus shows strong staining of the epithelium on

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KIF5B

Antigène: KIF5B (Kinesin Family Member 5B (KIF5B))

Autre désignation: KIF5B (KIF5B Produits)

Synonymes: anticorps KINH, anticorps KNS, anticorps KNS1, anticorps UKHC, anticorps Khc, anticorps AL022807, anticorps Khcs, anticorps Kns1, anticorps Ukhc, anticorps khc, anticorps KIF5A, anticorps kinesin family member 5B, anticorps kinesin heavy chain, anticorps kinesin-1, anticorps kinesin-1 heavy chain, anticorps kinesin family member 5B S homeolog, anticorps KIF5B, anticorps LOC411769, anticorps cgd6_2790, anticorps kin-1, anticorps Tb927.1.1350, anticorps LACBIDRAFT_305999, anticorps Khc, anticorps LOC100538629, anticorps Kif5b, anticorps kif5b.S

Sujet: Kinesins are a superfamily of microtubule-based motor proteins involved in a variety of cellular processes including the transport of organelles in eukaryotic cells and cell division. They typically consist of 2 identical, approximately 110- to 120-kD heavy chains and 2 identical, approximately 60- to 70-kD light chains. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.Synonyms: Conventional kinesin heavy chain, KIF5B, KNS, KNS1, Kinesin-1 heavy chain, UKHC, Ubiquitous kinesin heavy chain

ID gène: 3799

NCBI Accession: NP_004512

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization