Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène
CHMP5
(Charged Multivesicular Body Protein 5 (CHMP5))
anticorps SNF7DC2, anticorps cgi-34, anticorps hspc177, anticorps pnas-2, anticorps vps60, anticorps chmp5, anticorps zgc:64125, anticorps C9orf83, anticorps HSPC177, anticorps PNAS-2, anticorps Vps60, anticorps 2210412K09Rik, anticorps AW545668, anticorps RGD1305968, anticorps charged multivesicular body protein 5 S homeolog, anticorps charged multivesicular body protein 5b, anticorps charged multivesicular body protein 5, anticorps charged multivesicular body protein 5 L homeolog, anticorps chromatin modifying protein 5, anticorps chmp5.S, anticorps chmp5b, anticorps CHMP5, anticorps chmp5.L, anticorps chmp5, anticorps Chmp5
Sujet
CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo.Synonyms: C9orf83, CHMP-5, Charged multivesicular body protein 5, Chromatin-modifying protein 5, SNF7 domain-containing protein 2, SNF7DC2, Vacuolar protein-sorting-associated protein 60, Vps60, hVps60