Kallikrein 5 anticorps (Internal Region)
Aperçu rapide pour Kallikrein 5 anticorps (Internal Region) (ABIN374828)
Antigène
Voir toutes Kallikrein 5 (KLK5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- This antibody recognizes KLK5.
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Réactivité croisée (Details)
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Species reactivity (expected):Rat and Canine.
Species reactivity (tested):Human. -
Purification
- Affinity Chromatography.
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Immunogène
- Peptide with sequence KAGRDSCQGD, from the internal region of the protein sequence
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Indications d'application
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Peptide ELISA: 1/4000. Western Blot: 0.1-0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Kallikrein 5 (KLK5)
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Autre désignation
- KLK5 / Kallikrein-5
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Sujet
- Kallikrein 5 was originally described from the skin as an enzyme involved in turnover of the stratum corneum, and later cloned from human EST libraries as a Kallikrein like enzyme. The skin is known to contain trypsin like and chymotrypsin like proteinases of 32 kDa and 25 kDa respectively, and these were determined to be hK5 and hK7. Kallikrein 5 is found is greatest abundance in the skin, and also in the brain, with lesser signal in the kidney, lung, mammary gland, and testis. Human breast milk is reported to contain high levels of Kallikrein 5. Less stringent PCR detects hK5 in many tissues, and analysis of cell lines by Western blot shows that many cell lines make hK5.Synonyms: KLK-5, KLK-L2, Kallikrein-Like Protein 2, SCTE, Stratum corneum tryptic enzyme
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ID gène
- 25818
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NCBI Accession
- NP_001070959
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UniProt
- Q9Y337
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Pathways
- Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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