DLG1 anticorps (Internal Region)
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- Antigène Voir toutes DLG1 Anticorps
- DLG1 (Discs, Large Homolog 1 (DLG1))
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Épitope
- Internal Region
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Reactivité
- Humain, Rat, Souris
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DLG1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to DLG1.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence C-NSKTRDKGEIPDD, from the internal region of the protein sequence
- Top Product
- Discover our top product DLG1 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- DLG1 (Discs, Large Homolog 1 (DLG1))
- Autre désignation
- DLG1 (DLG1 Produits)
- Synonymes
- anticorps DLG1, anticorps Dlgh1, anticorps SAP97, anticorps B130052P05Rik, anticorps E-dlg/SAP97, anticorps SAP-97, anticorps mKIAA4187, anticorps DLGH1, anticorps dJ1061C18.1.1, anticorps hdlg, anticorps discs large MAGUK scaffold protein 1, anticorps discs, large homolog 1 (Drosophila), anticorps DLG1, anticorps Dlg1
- Sujet
- Synapse-associated protein (SAP) 97 is a 97 kDa membraneassociated synapse protein with extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminal. SAP97 consists of three 90 amino acid PDZ domains at its amino terminus, followed by a Src homology (SH) 3 domain, and a region with homology to guanylate kinases (GK). In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP97 is recruited to the submembranous cortical cytoskeleton at cell-cell contact sites as part of the E-cadherin complex. Co-expression of SAP97 and K+ channel results in the colocalization of these proteins in large round intracellular aggregates. SAP 97 has been shown to have functional homology to Drosophila tumor suppressor protein (DlgA), a PSD 95 related protein involved in maintaining integrity of epithelial and neuromuscular junctions. SAP97 interacts with TOPK and the HTLV-1 viral Tax and HPV-18 E6 papillomavirus (HPV) oncoproteins.Synonyms: Disks large homolog 1, SAP-97, Synapse-associated protein 97
- ID gène
- 1739
- NCBI Accession
- NP_001091894
- UniProt
- Q12959
- Pathways
- Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
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