PTP4A1 anticorps (C-Term)

N° du produit ABIN374988

Détail du produit anti-PTP4A1 anticorps

Antigène: PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PTP4A1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: KDSNGHRNNC CIQ

Specificité: This antibody reacts to PTP4A1 / PRL-1.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the C Terminus of the protein sequence (NP_003454.1). Genename: PTP4A1

Information d'application

Indications d'application: Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PTP4A1

Antigène: PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

Autre désignation: PTP4A1 / PRL1 (PTP4A1 Produits)

Synonymes: anticorps ptp4a1, anticorps MGC83351, anticorps hh72, anticorps prl1, anticorps prl-1, anticorps MGC79517, anticorps ptpcaax1, anticorps ptp(caax1), anticorps fb54d08, anticorps fc01c04, anticorps wu:fb54d08, anticorps wu:fc01c04, anticorps zgc:101726, anticorps Ptp4a1, anticorps PRL-1, anticorps PTP4A1, anticorps PRL1, anticorps DKFZp459E022, anticorps AA415290, anticorps AU019864, anticorps C130021B01, anticorps Prl-1, anticorps HH72, anticorps PTP(CAAX1), anticorps PTPCAAX1, anticorps protein tyrosine phosphatase type IVA, member 1, anticorps protein tyrosine phosphatase type IVA, member 1 L homeolog, anticorps protein tyrosine phosphatase 4a1, anticorps PTP4A1, anticorps ptp4a1.L, anticorps ptp4a1, anticorps Ptp4a1

Sujet: The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.Synonyms: PRL-1, PTP(CAAXI), PTPCAAX1, Protein tyrosine phosphatase type IVA 1, Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1

ID gène: 7803

NCBI Accession: NP_003454

UniProt: Q93096