GABRA4 anticorps (Internal Region)

N° du produit ABIN375085

Détail du produit anti-GABRA4 anticorps

Antigène: GABRA4 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))

Épitope: Internal Region

Reactivité: Humain, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GABRA4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to GABRA4.

Réactivité croisée (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-EKAKRKTSKPPQE, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/16000. Western blot: Approx.70 kDa band observed in Human Brain (Cerebellum and FrontalCortex) lysates (calculated MW of 61.0 kDa according to NP_000800.2). Recommended concentration: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: Human Cortex shows patchy staining near orat the neuronal cell membrane. Recommended concentration: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GABRA4

Antigène: GABRA4 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))

Autre désignation: GABRA4 (GABRA4 Produits)

Synonymes: anticorps GABRA4, anticorps Gabra-4, anticorps gamma-aminobutyric acid type A receptor alpha4 subunit, anticorps gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4, anticorps GABRA4, anticorps Gabra4

Sujet: GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.Synonyms: GABAA Receptor alpha-4, GABRA-4, Gamma-Aminobutyric Acid Receptor subunit Alpha-4

ID gène: 2557

NCBI Accession: NP_000800

UniProt: P48169

Pathways: Synaptic Membrane