SLC10A2
Reactivité: Souris, Humain
WB, ELISA, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps zgc:63998, anticorps ISBAT, anticorps ASBT, anticorps IBAT, anticorps ISBT, anticorps NTCP2, anticorps PBAM, anticorps solute carrier family 10 member 2, anticorps solute carrier family 10 (sodium/bile acid cotransporter), member 2, anticorps solute carrier family 10, member 2, anticorps SLC10A2, anticorps slc10a2, anticorps Slc10a2
Sujet
This gene encodes a sodium/bile acid cotransporter. This transporter is the primarymechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM), muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq]Synonyms: ASBT, Apical sodium-dependent bile acid transporter, IBAT, ISBT, Ileal Na(+)/bile acid cotransporter, Ileal sodium-dependent bile acid transporter, Ileal sodium/bile acid cotransporter, NTCP2, Na(+)-dependent ileal bile acid transporter, Sodium/taurocholate cotransporting polypeptide, Solute carrier family 10 member 2, ileal