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CD11b anticorps (PE)

ITGAM Reactivité: Souris FACS Hôte: Rat Monoclonal M1-70 PE
N° du produit ABIN375514
  • Antigène Voir toutes CD11b (ITGAM) Anticorps
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivité
    • 274
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    Souris
    Hôte
    • 152
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    Rat
    Clonalité
    • 274
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    Monoclonal
    Conjugué
    • 117
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    Cet anticorp CD11b est conjugé à/à la PE
    Application
    • 276
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    Flow Cytometry (FACS)
    Specificité
    Mouse/Human/Rhesus/Baboon/Rabbit CD11b, Mr 170 kDa
    Attributs du produit
    Rat Anti-Mouse CD11b-PE
    Purification
    Purified
    Immunogène
    C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
    Clone
    M1-70
    Isotype
    IgG2b
    Top Product
    Discover our top product ITGAM Anticorps primaire
  • Indications d'application
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, CY5, PE/CY7, APC/CY7, PACBLU, AF647 and AF700 0.3 g/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    In vitro and in vivo blocking

    Volume d'échantillon
    2 mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Antigène
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Autre désignation
    CD11b (ITGAM Produits)
    Synonymes
    anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
    Sujet
    CD11b, the integrin α M subunit, combines with CD18, the integrin β 2 subunit, to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1/CD54. Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 expression is rapidly up-regulated on neutrophils after activation and in the same time period that CD62L is shed from the cell surface. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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