CD11b anticorps

N° du produit ABIN375583

Cet anticorps Souris Monoclonal détecte spécifiquement CD11b dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD11b anticorps (ABIN375583)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Flow Cytometry (FACS)

Clone: ICRF44

Détail du produit anti-CD11b anticorps

Specificité: Human/Porcine/Rhesus/Cynomolgus/Chimpanzee/Baboon CD11b, Mr 165 kDa

Attributs du produit: Mouse Anti-Human CD11b-UNLB

Purification: Purified

Immunogène: Rheumatoid synovial cells and human monocytes

Isotype: IgG1

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, PACBLU, AF488 and AF647 10 L/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Commentaires:

Blocking Studies

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Agent conservateur: Without preservative

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: CD11b

Sujet: CD11b is the 165 kDa α M chain which combines with the CD18 β 2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b/Mac-1 α functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation