CD11b anticorps

N° du produit ABIN380068

Cet anticorps Souris Monoclonal détecte spécifiquement CD11b dans IHC et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour CD11b anticorps (ABIN380068)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: OX-42

Détail du produit anti-CD11b anticorps

Specificité: CD11b/c. OX-42 recognizes three major polypeptides of 160  kDa, 103  kDa and 95  kDa and a minor 133  kDa protein under non-reducing conditions. Under reducing conditions two major peptides of 163  kDa and 100  kDa and a minor 135  kDa peptide are detected. Antigen distribution: Isolated cells: OX-42 shows a similar reaction pattern to OX-41 on various isolated cells but stains bronchial lavage cells to a lesser degree. OX-42 inhibits complement mediated rosettes. Tissue sections: OX-42 is a most suitable marker for the identification of microglial cells and Kupffer cells. It also stains dendritic cells strongly. Only a subpopulation of alveolar macrophages is recognised. Specificity: Rat: granulocytes, macrophages, microglial cells. Other species: not tested

Purification: Purified

Immunogène: Peritoneal macrophages

Information d'application

Indications d'application: Approved: IHC, IHC-Fr (1:100 - 1:200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS  pH 7.2, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: CD11b + C

Sujet: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

ID gène: 3684

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation