SLC29A1 anticorps (AA 234-263)

N° du produit ABIN387941

Détail du produit anti-SLC29A1 anticorps

Antigène: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Épitope: AA 234-263

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC29A1 est non-conjugé

Application: Western Blotting (WB)

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the Central region of rat ENT1(O54698).

Clone: RB28016

Isotype: IgG

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-SLC29A1 (ABIN387941)

Niemann, Haufs-Brusberg, Puetz, Feickert, Jaeckstein, Hoffmann, Zurkovic, Heine, Trautmann, Müller, Tönjes, Schlein, Jafari, Eltzschig, Gnad, Blüher, Krahmer, Kovacs, Heeren, Pfeifer: "Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine." dans: Nature, (2022) (PubMed).

Ibarra, Pfeiffer: "Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance." dans: Journal of virology, Vol. 83, Issue 9, pp. 4538-47, (2009) (PubMed).

Détails sur SLC29A1

Antigène: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Autre désignation: ENT1 (SLC29A1 Produits)

Synonymes: anticorps ENT1, anticorps rENT1, anticorps 1200014D21Rik, anticorps AA407560, anticorps solute carrier family 29 member 1 (Augustine blood group), anticorps solute carrier family 29 member 1, anticorps solute carrier family 29 (nucleoside transporters), member 1, anticorps SLC29A1, anticorps Slc29a1

Sujet: ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.

Poids moléculaire: 50219

ID gène: 2030

NCBI Accession: NP_001071642, NP_001071643, NP_001071644, NP_001071645, NP_004946

UniProt: Q99808

Pathways: Carbohydrate Homeostasis, Synaptic Membrane