USP8 anticorps (N-Term)

N° du produit ABIN388890

Cet anticorps anti-USP8 est un anticorps Lapin Polyclonal détectant USP8 dans WB. Adapté pour Humain.

Aperçu rapide pour USP8 anticorps (N-Term) (ABIN388890)

Antigène: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP8 est non-conjugé

Application: Western Blotting (WB)

Clone: RB4284

Détail du produit anti-USP8 anticorps

Épitope: AA 1-30, N-Term

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This USP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USP8.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur USP8

Antigène: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Autre désignation: USP8

Sujet: USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.

Poids moléculaire: 127523

ID gène: 9101

NCBI Accession: NP_001122082, NP_001122083, NP_005145

UniProt: P40818