This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This SULT2B1a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SULT2B1a/b.
anticorps HSST2, anticorps AI326997, anticorps BB173635, anticorps ST2B1, anticorps SULT2B, anticorps SULT2B1, anticorps MGC79784, anticorps sulfotransferase family 2B member 1, anticorps sulfotransferase family, cytosolic, 2B, member 1, anticorps sulfotransferase family 2B member 1 L homeolog, anticorps SULT2B1, anticorps Sult2b1, anticorps sult2b1, anticorps sult2b1.L
Sujet
Cytosolic sulfotransferases (STs or SULTs) catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. Her et al. (1998) identified an EST with homology to ST enzymes. By PCR with human placental and prostate cDNA as template, they isolated 2 alternatively spliced cDNAs, identical throughout most of their sequences, but having different 5-prime ends. The shorter cDNA, SULT2B1a, encodes a protein of 350 amino acids, the longer cDNA, SULT2B1b, encodes a 365-amino acid protein. Genomic PCR analysis revealed that the gene encoding both cDNAs, SULT2B1, contains 7 exons, with 2 alternative first exons being used to generate SULT2B1a and SULT2B1b. Northern blot analysis revealed that the SULT2B1 gene is expressed as a 1.4-kb transcript predominantly in prostate, placenta, and trachea.