ERBB4 anticorps (pTyr1162)

N° du produit ABIN389572

Cet anticorps Lapin Polyclonal détecte spécifiquement ERBB4 dans WB, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour ERBB4 anticorps (pTyr1162) (ABIN389572)

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERBB4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB5687

Détail du produit anti-ERBB4 anticorps

Épitope: pTyr1162

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HER4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1162 of human HER4.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:500. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ERBB4 (ABIN389572)

Prickett, Agrawal, Wei, Yates, Lin, Wunderlich, Cronin, Cruz, Rosenberg, Samuels: "Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4." dans: Nature genetics, Vol. 41, Issue 10, pp. 1127-32, (2009) (PubMed).

Burns, Li, Cheney, Ou, Franlin-Pfeifer, Kuklin, Zhang: "Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 57, Issue 3, pp. 257-64, (2009) (PubMed).

Détails sur ERBB4

Antigène: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Autre désignation: HER4

Sujet: HER4/ERBB4 is a member of the type I receptor tyrosine kinase subfamily that includes EGFR, ERBB2 and ERBB3. It is a receptor for NDF/heregulin.

Poids moléculaire: 146808

ID gène: 2066

NCBI Accession: NP_001036064, NP_005226

UniProt: Q15303

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway