SMAD4 anticorps (pThr277)

N° du produit ABIN389658

Cité dans 1 publication. Cet anticorps anti-SMAD4 Polyclonal Lapin (Clone RB07971) (ABIN389658) détecte spécifiquement SMAD4 dans WB, ELISA, IF, IHC (p) et DB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour SMAD4 anticorps (pThr277) (ABIN389658)

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone: RB07971

Détail du produit anti-SMAD4 anticorps

Épitope: pThr277

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:500
IHC-P: 1:10-50
IF: 1:10-50
DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-SMAD4 (ABIN389658)

Arjunan, Gnanaprakasam, Ananth, Romej, Rajalakshmi, Prasad, Martin, Gurusamy, Thangaraju, Bhutia, Ganapathy: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." dans: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).

Détails sur SMAD4

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation: SMAD4

Sujet: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Poids moléculaire: 60439

ID gène: 4089

NCBI Accession: NP_005350

UniProt: Q13485

Pathways: Cycle Cellulaire, Chromatin Binding, Autophagy