NOTCH3 anticorps (AA 47-156)
Aperçu rapide pour NOTCH3 anticorps (AA 47-156) (ABIN5542534)
Antigène
Voir toutes NOTCH3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 47-156
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Fonction
- Notch3 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.
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Isotype
- IgG2a
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Indications d'application
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- NOTCH3 (Notch 3 (NOTCH3))
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Autre désignation
- Notch3
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Sujet
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This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
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Poids moléculaire
- 243.6 kDa
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ID gène
- 4854
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UniProt
- Q9UM47
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Pathways
- Signalisation Notch
Antigène
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