PLAT anticorps (AA 371-399)
Aperçu rapide pour PLAT anticorps (AA 371-399) (ABIN390746)
Antigène
Voir toutes PLAT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 371-399
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This TPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-399 amino acids from the Central region of human TPA.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- PLAT (Plasminogen Activator, Tissue (PLAT))
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Autre désignation
- TPA
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Sujet
- TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.
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Poids moléculaire
- 62917
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ID gène
- 5327
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NCBI Accession
- NP_000921, NP_127509
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UniProt
- P00750
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Pathways
- Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
Antigène
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