DIO1 anticorps (N-Term)

N° du produit ABIN390946

Détail du produit anti-DIO1 anticorps

Antigène: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Épitope: AA 30-57, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIO1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1.

Clone: RB21147

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur DIO1

Antigène: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Autre désignation: DIO1 (DIO1 Produits)

Synonymes: anticorps 5DI, anticorps TXDI1, anticorps ITDI1, anticorps D1, anticorps DIOI, anticorps Deio1, anticorps cb685, anticorps zgc:92323, anticorps iodothyronine deiodinase 1, anticorps type I iodothyronine deiodinase-like, anticorps deiodinase, iodothyronine, type I, anticorps deiodinase, iodothyronine type 1 L homeolog, anticorps DIO1, anticorps LOC100231867, anticorps Dio1, anticorps dio1.L, anticorps dio1

Sujet: DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).

Poids moléculaire: 28924

ID gène: 1733

NCBI Accession: NP_000783, NP_001034804, NP_001034805, NP_998758

UniProt: P49895

Pathways: Hormone Activity