PDGFRA anticorps (AA 746-775)
Aperçu rapide pour PDGFRA anticorps (AA 746-775) (ABIN392027)
Antigène
Voir toutes PDGFRA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 746-775
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Homologie
- M, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 746-775 amino acids from human PDGFRA.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. IHC-P: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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Autre désignation
- PDGFRA
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Sujet
- PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
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Poids moléculaire
- 122670
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ID gène
- 5156
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NCBI Accession
- NP_006197
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UniProt
- P16234
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
Antigène
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