SMAD4 anticorps (AA 255-284)

N° du produit ABIN392165

1 publication est disponible pour ce produit. L’anticorps anti-SMAD4 Polyclonal produit chez le Lapin a été validé pour WB et IF. Il convient pour la détection de SMAD4 dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour SMAD4 anticorps (AA 255-284) (ABIN392165)

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: RB14714

Détail du produit anti-SMAD4 anticorps

Épitope: AA 255-284

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SMAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from human SMAD4.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-SMAD4 (ABIN392165)

Lessard, Rivas, Alves-Wagner, Hirshman, Gallagher, Constantin-Teodosiu, Atkins, Greenhaff, Qi, Gustafsson, Fielding, Timmons, Britton, Koch, Goodyear: "Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks." dans: Diabetes, Vol. 62, Issue 8, pp. 2717-27, (2013) (PubMed).

Détails sur SMAD4

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation: SMAD4

Sujet: SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Poids moléculaire: 60439

ID gène: 4089

NCBI Accession: NP_005350

UniProt: Q13485

Pathways: Cycle Cellulaire, Chromatin Binding, Autophagy