TRPM6 anticorps (AA 317-348)

N° du produit ABIN392616

Détail du produit anti-TRPM6 anticorps

Antigène: TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))

Épitope: AA 317-348

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPM6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TRPM6 (CHAK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-348 amino acids from the Central region of human TRPM6 (CHAK2).

Clone: RB3407

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-TRPM6 (ABIN392616)

Furukawa, Fujii, Manabe, Matsunaga, Endo, Hasegawa, Ito, Yamaguchi, Yamazaki, Ikari: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." dans: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).

Ikari, Okude, Sawada, Takahashi, Sugatani, Miwa: "Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A." dans: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 377, Issue 4-6, pp. 333-43, (2008) (PubMed).

Ikari, Okude, Sawada, Yamazaki, Sugatani, Miwa: "TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells." dans: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1129-33, (2008) (PubMed).

Détails sur TRPM6

Antigène: TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))

Autre désignation: TRPM6 (CHAK2) (TRPM6 Produits)

Synonymes: anticorps TRPM6, anticorps CHAK2, anticorps HMGX, anticorps HOMG, anticorps HOMG1, anticorps HSH, anticorps TRPM6/CHAK2, anticorps transient receptor potential cation channel subfamily M member 6, anticorps transient receptor potential cation channel, subfamily M, member 6, anticorps TRPM6, anticorps Trpm6

Sujet: CHAK2 is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes.

Poids moléculaire: 231708

ID gène: 140803

NCBI Accession: NP_001170781, NP_001170782, NP_060132

UniProt: Q9BX84