EPS8 anticorps (N-Term)

N° du produit ABIN392773

Détail du produit anti-EPS8 anticorps

Antigène: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Épitope: AA 9-39, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPS8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EPS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human EPS8.

Clone: RB4003

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:25. WB: 1:2000. WB: 1:2000. WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-EPS8 (ABIN392773)

Nasr, Mukhopadhyay, Zhang, Katzenstein: "Immunohistochemical markers in diagnosis of papillary thyroid carcinoma: Utility of HBME1 combined with CK19 immunostaining." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 19, Issue 12, pp. 1631-7, (2006) (PubMed).

Détails sur EPS8

Antigène: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Autre désignation: EPS8 (EPS8 Produits)

Synonymes: anticorps AW261790, anticorps MGC81285, anticorps MGC146320, anticorps zgc:56041, anticorps epidermal growth factor receptor pathway substrate 8, anticorps epidermal growth factor receptor pathway substrate 8 L homeolog, anticorps EPS8, anticorps Eps8, anticorps eps8.L, anticorps eps8

Sujet: Upon binding to EGF receptor, EPS8 enhances EGF-dependent mitogenic signals. It can bind multiple cellular targets. EPS8 is expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. It is expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells. EPS8 is phosphorylated by several receptor tyrosine kinases. The protein contains 1 PH domain and 1 SH3 domain.

Poids moléculaire: 91882

ID gène: 2059

NCBI Accession: NP_004438

UniProt: Q12929

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization