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PTP4A3 anticorps

PTP4A3 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB7265 unconjugated
N° du produit ABIN392854
  • Antigène Voir toutes PTP4A3 Anticorps
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    Reactivité
    • 45
    • 23
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 42
    • 3
    Lapin
    Clonalité
    • 43
    • 2
    Polyclonal
    Conjugué
    • 23
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTP4A3 est non-conjugé
    Application
    • 31
    • 17
    • 10
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PRL3 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human PRL3.
    Clone
    RB7265
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PTP4A3 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    Autre désignation
    PRL3 (PTP4A3 Produits)
    Synonymes
    anticorps PRL-3, anticorps PRL-R, anticorps PRL3, anticorps wu:fc54b05, anticorps wu:fv52d11, anticorps zgc:77109, anticorps prl-3, anticorps prl3, anticorps ptpcaax3, anticorps PTP4A3, anticorps AV088979, anticorps Prl-3, anticorps pPtp4a3, anticorps protein tyrosine phosphatase type IVA, member 3, anticorps protein tyrosine phosphatase type IVA, member 3 L homeolog, anticorps protein tyrosine phosphatase 4a3, anticorps PTP4A3, anticorps ptp4a3, anticorps ptp4a3.L, anticorps Ptp4a3
    Sujet
    The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. PRL-3 expression was found to be up-regulated in human liver carcinoma compared with normal liver. Its expression in colorectal cancers may contribute to the establishment of liver metastasis. In a different study, PRL-3 is found to be expressed in tumor metastasis and vasculature, regardless of the tumor source.
    Poids moléculaire
    19535
    ID gène
    11156
    NCBI Accession
    NP_009010, NP_116000
    UniProt
    O75365
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