CENPQ anticorps

N° du produit ABIN401060

Détail du produit anti-CENPQ anticorps

Antigène: CENPQ (Centromere Protein Q (CENPQ))

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Cheval, Macaque

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPQ est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody is specific for CENP-Q protein.

Réactivité croisée (Details): Species reactivity (expected):Macaque, Horse, Bovine, Canine, Porcine, Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography on protein A

Immunogène: Prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1: 20,000 - 1: 30,000. Immunofluorescence. Western Blot: 1: 2,000 - 1: 2,500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.15 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur CENPQ

Antigène: CENPQ (Centromere Protein Q (CENPQ))

Autre désignation: CENP-Q (CENPQ Produits)

Synonymes: anticorps C6orf139, anticorps CENP-Q, anticorps 2610528M18Rik, anticorps centromere protein Q, anticorps CENPQ, anticorps cenpq, anticorps Cenpq

Sujet: Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.Synonyms: C6orf139, CENPQ, Centromere protein Q, chromosome 6 open reading frame 139

ID gène: 55166

NCBI Accession: NP_060602

UniProt: Q7L2Z9