NIPBL anticorps (AA 344-356)

N° du produit ABIN401167

Détail du produit anti-NIPBL anticorps

Antigène: NIPBL (Nipped-B like Protein (NIPBL))

Épitope: AA 344-356

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Orang-Utan

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NIPBL est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is directed against IDN3 protein.

Réactivité croisée (Details): Species reactivity (expected):Rat, Mouse, Canine, Bovine, Orangutan.
Species reactivity (tested):Human.

Purification: Affinity Purified

Immunogène: Synthetic peptide corresponding to amino acids 344-356 of Human IDN3

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/2000 - 1/10000. Western Blot: 1/500 - 1/3000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.6 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur NIPBL

Antigène: NIPBL (Nipped-B like Protein (NIPBL))

Autre désignation: NIPBL (NIPBL Produits)

Synonymes: anticorps CDLS, anticorps CDLS1, anticorps IDN3, anticorps IDN3-B, anticorps Scc2, anticorps SCC2W, anticorps scc2, anticorps nipbl, anticorps scc2-2, anticorps NIPBL, anticorps nipbla, anticorps wu:fi33d08, anticorps 4921518A06Rik, anticorps 4933421G18Rik, anticorps C79399, anticorps Idn3, anticorps NIPBL, cohesin loading factor, anticorps Nipped-B homolog-like, anticorps NIPBL, cohesin loading factor S homeolog, anticorps nipped-B homolog b (Drosophila), anticorps nipped-B-like protein A, anticorps Nipped-B homolog (Drosophila), anticorps NIPBL, anticorps NIPBLL, anticorps nipbl.S, anticorps LOC427439, anticorps nipblb, anticorps LOC100164947, anticorps nipbl, anticorps Nipbl

Sujet: IDN3 (also known as Colon tumor susceptibility 2, DKFZp434L1319, FLJ13648, Mis 4, Scc-2, Delangin and Sister chromatid cohesion protein) is the mammalian homologue of Scc2 in S. cerevisiae and Mis4 in S. pombe. In yeast, this factor was originally identified genetically as being involved in sister chromatid cohesion, subsequent work has determined that it is not involved in cohesion directly but is required for the loading of cohesins onto chromatin during S phase. It shares 37 % sequence identity with Nipped-B gene product of Drosophila, which facilitates enhancerpromoter communication of remote enhancers. The Drosophila protein is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. IDN3 is a nuclear protein that is widely expressed and found at the highest levels in heart, skeletal muscle, fetal and adult liver, and fetal and adult kidney. The protein is also found, albeit at lower levels of expression in thymus, placenta, peripheral leukocyte and small intestine. Multiple isoforms of the protein have been reported.Synonyms: Delangin, IDN3, Nipped-B-like protein, SCC2 homolo

ID gène: 25836

NCBI Accession: NP_056199

UniProt: Q6KC79

Pathways: Sensory Perception of Sound, Stem Cell Maintenance