GGA1 anticorps (AA 336-352)

N° du produit ABIN401291

Détail du produit anti-GGA1 anticorps

Antigène: GGA1 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))

Épitope: AA 336-352

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GGA1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is directed against GGA1 protein.

Réactivité croisée (Details): Species reactivity (expected):Bovine, Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding to amino acids 336-352 of Human GGA-1

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/10,000 - 1/50,000. Western Blot: 1/500 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.35 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur GGA1

Antigène: GGA1 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))

Autre désignation: GGA1 (GGA1 Produits)

Synonymes: anticorps 4930406E12Rik, anticorps AU016030, anticorps AW209092, anticorps fb33h10, anticorps im:6912200, anticorps wu:fb33h10, anticorps zgc:101044, anticorps putative golgi associated, gamma adaptin ear containing,arf binding protein 1 (gga1), anticorps golgi associated, gamma adaptin ear containing, ARF binding protein 1, anticorps golgi-associated, gamma adaptin ear containing, ARF binding protein 1, anticorps Smp_164030, anticorps Gga1, anticorps gga1, anticorps GGA1

Sujet: GGA1 (also known as ADP-ribosylation factor binding protein, Golgi-localized, gamma earcontaining, ARF-binding protein 1, Gamma-adaptin related protein 1) plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. This protein mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. GGA1 is a monomeric protein that interacts with NECAP1, GGA2 and GGA3 as well as RABEP1, RABGEF1 and type-I membrane proteins SORT1, SORL1, LRP3, M6PR/CDMPR, IGF2R/CI-MPR and BACE1. GGA1 is a ubiquitously membrane-associated protein that is localized to TGN and endosomes. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: ADP-ribosylation factor-binding protein GGA1, Gamma-adaptin-related protein 1, Golgi-localized gamma ear-containing ARF-binding protein 1

ID gène: 26088

NCBI Accession: NP_001001560

UniProt: Q9UJY5