PDGFRA anticorps (APC)

N° du produit ABIN452286

Détail du produit anti-PDGFRA anticorps (APC)

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDGFRA est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Specificité: This Mouse monoclonal antibody 16A1 recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.

Attributs du produit: Synonyms: PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A

Purification: Size-Exclusion Chromatography

Immunogène: CD140a-transfected NIH 3T3 cells

Clone: 16A1

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 10 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension. The content of a vial (0.25 ml) is sufficient for 25 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PDGFRA

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Autre désignation: CD140a / PDGFRA (PDGFRA Produits)

Synonymes: anticorps AI115593, anticorps CD140a, anticorps Pdgfr-2, anticorps APDGFR, anticorps PDGFACE, anticorps CD140A, anticorps PDGFR-2, anticorps PDGFR2, anticorps RHEPDGFRA, anticorps PDGFR, anticorps PDGFR-A, anticorps platelet derived growth factor receptor alpha, anticorps platelet derived growth factor receptor, alpha polypeptide, anticorps platelet-derived growth factor receptor, alpha polypeptide L homeolog, anticorps platelet-derived growth factor receptor, alpha polypeptide, anticorps PDGFRA, anticorps Pdgfra, anticorps pdgfra.L

Sujet: CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha

ID gène: 5156

UniProt: P16234

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling