PDGFRA anticorps

N° du produit ABIN452289

Cet anticorps anti-PDGFRA Monoclonal Souris (Clone 16A1) (ABIN452289) détecte spécifiquement PDGFRA dans FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PDGFRA anticorps (ABIN452289)

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDGFRA est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 16A1

Détail du produit anti-PDGFRA anticorps

Specificité: The 16A1 antibody recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.

Attributs du produit: Synonyms: PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A

Purification: Protein A affinity chromatography

Pureté: > 95 % by SDS-PAGE

Immunogène: CD140a-transfected NIH 3T3 cells

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 2 μg/mLImmunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PDGFRA

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Autre désignation: CD140a / PDGFRA

Sujet: CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha

ID gène: 5156

UniProt: P16234

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling