Reactive to tyrosine699 phosphorylated Human STAT5b peptide fragment conjugated with KLH or the peptide-BSA conjugate, but not reactive to unconjugated KLH or BSA.
Attributs du produit
Synonyms: STAT-5B, Signal transducer and activator of transcription 5B
Purification
Affinity chromatography on Protein G
Immunogène
Peptide of a phosphorlylated fragment of STAT5b(p-T694) , conjugated with KLH
Indirect ELISA: The suggested antigen coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 carbonate buffer, 100 μL/well Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL
Buffer
0.01 M PBS, pH 7.2 without preservatives
Agent conservateur
Without preservative
Stock
-20 °C
Stockage commentaire
Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Antigène
STAT5B
(Signal Transducer and Activator of Transcription 5B (STAT5B))
anticorps STAT5, anticorps stat5, anticorps STAT5A, anticorps STAT5B, anticorps signal transducer and activator of transcription 5B, anticorps signal transducer and activator of transcription 5B S homeolog, anticorps Signal transducer and activator of transcription 5B, anticorps STAT5B, anticorps Stat5b, anticorps stat5b.S, anticorps LOC490969, anticorps sta5b, anticorps LOC100566752, anticorps LOC100052954
Sujet
Stat5b is a transcription factor that is activated in response to extra-cellular stimuli including IL-2, IL-4, MCSF and a variety of growth factors. In the process, receptor associated kinases phosphorylate Stat5b. Stat5b, then, forms dimers and translocates to nucleus. Inside nucleus, Stat5b binds to the promoter region on various genes to regulate biological processes such as apoptosis, T cell receptor signalling, and adult mammary gland development. Fusion of Stat5b to retinoic acid receptor-alpha (RARα) gene was identified in a small subgroup of acute promyelocytic leukemia patients.Synonyms: STAT-5B, Signal transducer and activator of transcription 5B