STAT5B anticorps (pThr694)

N° du produit ABIN452649

Cet anticorps anti-STAT5B Monoclonal Souris (Clone A4B9) (ABIN452649) détecte spécifiquement STAT5B dans EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour STAT5B anticorps (pThr694) (ABIN452649)

Antigène: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp STAT5B est non-conjugé

Application: Enzyme Immunoassay (EIA)

Clone: A4B9

Détail du produit anti-STAT5B anticorps

Épitope: pThr694

Specificité: Reactive to tyrosine699 phosphorylated Human STAT5b peptide fragment conjugated with KLH or the peptide-BSA conjugate, but not reactive to unconjugated KLH or BSA.

Attributs du produit: Synonyms: STAT-5B, Signal transducer and activator of transcription 5B

Purification: Affinity chromatography on Protein G

Immunogène: Peptide of a phosphorlylated fragment of STAT5b(p-T694) , conjugated with KLH

Isotype: IgG1

Information d'application

Indications d'application: Indirect ELISA: The suggested antigen coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 carbonate buffer, 100 μL/well
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2 without preservatives

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur STAT5B

Antigène: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Autre désignation: STAT5B

Sujet: Stat5b is a transcription factor that is activated in response to extra-cellular stimuli including IL-2, IL-4, MCSF and a variety of growth factors. In the process, receptor associated kinases phosphorylate Stat5b. Stat5b, then, forms dimers and translocates to nucleus. Inside nucleus, Stat5b binds to the promoter region on various genes to regulate biological processes such as apoptosis, T cell receptor signalling, and adult mammary gland development. Fusion of Stat5b to retinoic acid receptor-alpha (RARα) gene was identified in a small subgroup of acute promyelocytic leukemia patients.Synonyms: STAT-5B, Signal transducer and activator of transcription 5B

ID gène: 6777

UniProt: P51692

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation