LNX1 anticorps

N° du produit ABIN4620358

Détail du produit anti-LNX1 anticorps

Antigène: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LNX1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects LNX1, expressed in heart, placenta, kidney, pancreas and brain.

Purification: Affinty chromatography

Immunogène: Synthetic peptide derived from the human LNX1 protein

Information d'application

Indications d'application: Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur LNX1

Antigène: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Autre désignation: LNX1 (LNX1 Produits)

Synonymes: anticorps LNX1, anticorps fj78f06, anticorps lnx, anticorps si:dkey-12h2.1, anticorps wu:fj78f06, anticorps zgc:152906, anticorps Lnx, anticorps LNX, anticorps MPDZ, anticorps PDZRN2, anticorps ligand of numb-protein X 1, anticorps LNX1, anticorps lnx1, anticorps Lnx1

Sujet: LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.Synonyms: E3 ubiquitin-protein ligase LNX, LNX, LNX-1, Ligand of Numb-protein X 1, Numb-binding protein 1

ID gène: 84708

NCBI Accession: NP_001119800

UniProt: Q8TBB1